Make.com WhatsApp Automation: Build Business Messaging Workflows

WhatsApp automation in Make.com enables businesses to send automated messages, build support bots, run appointment reminders, and create personalised outreach at scale. This guide covers how to connect WhatsApp to Make.com workflows using Twilio and the WhatsApp Business API.

MJK Supplies · Jun 12, 2026 · 11 min read

ShareX in f ↗

Make.com WhatsApp Automation: Build Business Messaging Workflows

WhatsApp Integration Options in Make.com

Make.com connects to WhatsApp through:

Twilio for WhatsApp: The most common approach. Twilio provides a WhatsApp Business API wrapper. Make.com has a native Twilio module. Easy to set up; per-message pricing.

360dialog: A Meta-approved WhatsApp Business Solution Provider. Direct API with higher throughput for enterprise.

WhatsApp Business API (direct): Requires Meta Business verification. Direct integration via Make's HTTP module.

For most businesses, Twilio is the fastest path to working WhatsApp automation.

Setting Up Twilio WhatsApp in Make.com

Prerequisites:

Twilio account (free to start)
WhatsApp Sandbox enabled in Twilio Console
For production: WhatsApp Business number approved by Meta via Twilio

In Make.com:

Add Twilio module → Connection → enter Account SID and Auth Token from Twilio Console
Select action: "Create a Message"
Set:

- To: whatsapp:+1234567890 - From: whatsapp:+your-twilio-number - Body: message text

Receiving WhatsApp messages: In Twilio Console → Messaging → WhatsApp → Sandbox → set webhook to a Make.com Webhook URL.

Add Webhook trigger in Make.com → copy URL → paste in Twilio.

Now Make.com fires whenever a WhatsApp message is received.

WhatsApp Support Bot

Scenario: AI-powered WhatsApp support

Webhook trigger: Inbound WhatsApp message (Twilio webhook to Make.com)
Data Store (search): Look up conversation history by phone number
HTTP (Claude API): Send conversation history + new message + system prompt
Data Store (update): Save updated conversation
Twilio: Send reply message via WhatsApp

Claude system prompt for WhatsApp:

You are a support assistant for [Company] responding via WhatsApp. Keep responses under 200 words — this is a mobile messaging app. Be helpful and specific. Use simple, direct language. Our product knowledge: [paste your documentation]

Conversation history data structure:

{ "phone": "+1234567890", "history": [ {"role": "user", "content": "How do I reset my password?"}, {"role": "assistant", "content": "To reset your password, go to..."} ], "last_active": "2026-06-23T10:30:00Z" }

Appointment Reminders

Automated WhatsApp appointment reminders:

Trigger: Make.com Schedule (run every hour)
Airtable (search): Find appointments starting in next 24 hours with no reminder sent
Iterator: Process each appointment
Router: Based on appointment type (consultation, demo, call)
Twilio (WhatsApp): Send personalised reminder message
Airtable (update): Mark reminder as sent

Message template:

Hi {{name}} 👋 Reminder: You have a {{appointment_type}} with {{agent_name}} tomorrow at {{time}}. Reply YES to confirm or RESCHEDULE to pick a new time. [Company Name]

Reply handler Scenario: When customer replies:

Twilio webhook → Make.com
Check if body = "YES" → Update Airtable: confirmed
Check if body = "RESCHEDULE" → Send Calendly link + update status

Lead Follow-Up via WhatsApp

WhatsApp has dramatically higher open rates than email (90%+ vs 20%). Use it for lead follow-up:

HubSpot trigger: New lead (form submission)
Wait: 5 minutes delay
Claude HTTP: Generate personalised first message based on lead source and company
Twilio: Send WhatsApp message

Note: Only send WhatsApp messages to prospects who have opted in or provided their number for this purpose. WhatsApp Business policy requires prior consent.

Multi-Language Support

For global businesses:

Detect language from incoming message (Claude: "What language is this message in?")
Router: branch by language
Claude: respond in appropriate language
Twilio: send localised response